PSI Structural Biology Knowledgebase

PSI Nature Structural Biology Knowledgebase
Header Icons
 

Featured System

Featured Molecule

Signaling with DivL

DivL shares many structural features with other bacterial signaling proteins, but has been modified by evolution to reverse the typical directionality of signaling.

Read More

Research Advances

  • Signaling Securing LipidProtein Partnership

    Signaling: Securing Lipid-Protein Partnership
    Crystal structures provide a glimpse into how phosphoinositides stabilize nuclear hormones.

    Read More
  • Signaling A Platform for Opposing Functions

    Signaling: A Platform for Opposing Functions
    A modeled structure reveals the regulatory complexities of a TORC1-interacting complex.

    Read More

Technical Highlights

  • CryoEM Beyond 3197 Resolution

    Cryo-EM Beyond 3-Å Resolution
    The 2.8-Å resolution cryo-EM reconstruction of a thermophilic 20S proteasome identifies rotamers and water molecules.

    Read More
  • A Solution for NearAtomic Resolution CryoEM

    A Solution for Near-Atomic Resolution Cryo-EM
    Two methods for macromolecular structure determination via near-atomic resolution cryo-EM help fill a resolution gap.

    Read More



Latest PSI Results

New structures last month:21
Total structures to date:6840
Total distinct structures:5457
Total community structures:597

Latest Structures

 

Protein Structure Initiative Corner

Collaborative Network

Publications

Search through over 2000 peer-reviewed publications by the PSI Network

Latest News

News from the Protein Structure Initiative and Nature

Community Nominations

Nominate proteins for structure determination by the PSI

SBKB Tools

Sequence Analysis: Use PSI tools to evaluate your constructs for structure determination

Functional Sleuth: See progress in characterizing structures of unknown function

Visualization Tool: See charts of functions of determinated structures