PSI Structural Biology Knowledgebase

PSI Nature Structural Biology Knowledgebase
Header Icons
 

Current Focus

Membrane Proteome

Featured System

Featured Molecule

Glucagon Receptor

PSI researchers have solved the structures of a GPCR that binds to peptide hormones, revealing new modes of GPCR recognition.

Read More

Research Advances

  • Membrane Proteome A Cap on Transport

    Membrane Proteome: A Cap on Transport
    Structural and biophysical analyses of a membrane carrier ectodomain reveal a Ca2+-dependent switch that regulates ATP flux across the mitochondrial inner membrane.

    Read More
  • Membrane Proteome Pumping Out Heavy Metal

    Membrane Proteome: Pumping Out Heavy Metal
    Crystal structures of a heavy-metal efflux pump reveal intermediate transport states.

    Read More

Technical Highlights

  • Membrane Proteome Microcrystals Yield Big Data

    Membrane Proteome: Microcrystals Yield Big Data
    An X-ray free-electron laser helps determine the first room-temperature structure of a G protein-coupled receptor.

    Read More
  • Combining Methods to Solve Protein Assemblies

    Combining Methods to Solve Protein Assemblies
    A hybrid approach that integrates four mass spectrometry methods with structural modeling takes on tough protein complexes.

    Read More



Latest PSI Results

New structures last month:28
Total structures to date:6528
Total distinct structures:5399
Total community structures:564

Latest Structures

 

Protein Structure Initiative Corner

Collaborative Network

Publications

Search through over 2000 peer-reviewed publications by the PSI Network

Latest News

News from the Protein Structure Initiative and Nature

Community Nominations

Nominate proteins for structure determination by the PSI

SBKB Tools

Sequence Analysis: Use PSI tools to evaluate your constructs for structure determination

Functional Sleuth: See progress in characterizing structures of unknown function

Visualization Tool: See charts of functions of determinated structures