PSI Structural Biology Knowledgebase

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Special: Retrospective

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Community-Nominated Targets

The Community-Nominated Targets program has allowed PSI to collaborate with researchers on hundreds of systems of high biological significance.

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Research Advances

  • Drug Discovery Solving the Structure of an Antihypertension Drug Target

    Drug Discovery: Solving the Structure of an Anti-hypertension Drug Target
    Serial femtosecond crystallography is used to solve the structure of angiotensin II type 1 receptor.

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  • Retrospective 7000 Structures Closer to Understanding Biology

    Retrospective: 7,000 Structures Closer to Understanding Biology
    As PSI:Biology comes to a close this month, we take a look back at all the biological advances made by the PSI Network.

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Technical Highlights

  • Retrospective Producing Proteins the PSIBiology Way

    Retrospective: Producing Proteins the PSI:Biology Way
    PSI:Biology developed new expression vectors and other tools and tricks to obtain samples of its challenging protein targets.

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  • Retrospective Bigger Faster Better Structure and Function Determination

    Retrospective: Bigger, Faster, Better Structure and Function Determination
    PSI:Biology employed cutting-edge technologies to obtain structures of complex targets.

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Latest PSI Results

New structures last month:23
Total structures to date:6880
Total distinct structures:5455
Total community structures:599

Latest Structures


Protein Structure Initiative Corner

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Search through over 2000 peer-reviewed publications by the PSI Network

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News from the Protein Structure Initiative and Nature

Community Nominations

Nominate proteins for structure determination by the PSI

SBKB Tools

Sequence Analysis: Use PSI tools to evaluate your constructs for structure determination

Functional Sleuth: See progress in characterizing structures of unknown function

Visualization Tool: See charts of functions of determinated structures