Community Nominated Targets proposal system

The PSI:Biology Network invites the community to benefit from its facilities and nominate proteins for structural determination. Participating centers are accepting proposals of collaboration for X-ray crystallography or NMR projects for protein structures of high biological significance. Such projects can include novel proteins, complexes, ligand-bound structures, and membrane proteins.

Please contact one of the participating centers above and discuss your project with them prior to submitting your proposal. Accepted proposals will adhere to PSI policies on data sharing, including deposition of coordinates to the PDB for immediate release. Note that while the centers will make good faith attempts to obtain a structure, a successful result cannot be guaranteed.

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To submit target nominations to the PSI:Biology Centers, please login here.

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10 most recent released structures


PDBID: 4JXI
TargetID: NESG-OR184
Title: Directed evolution and rational design of a de novo designed esterase toward improved catalysis. Northeast Structural Genomics Consortium (NESG) Target OR184

PDBID: 4JVV
TargetID: NESG-OR273
Title: Crystal structure of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1, covalently bound with diisopropyl fluorophosphate (DFP), Northeast Structural Genomics Consortium (NESG) Target OR273

PDBID: 4K0C
TargetID: NESG-OR317
Title: Crystal Structure of the computationally designed serine hydrolase. Northeast Structural Genomics Consortium (NESG) Target OR317

PDBID: 4JON
TargetID: JCSG-424890
Title: Crystal structure of a centrosomal protein 170kDa, transcript variant beta (CEP170) from Homo sapiens at 2.15 A resolution (PSI Community Target, Sundstrom)

PDBID: 4JLL
TargetID: NESG-OR273
Title: Crystal Structure of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1 covalently bound with FP-alkyne, Northeast Structural Genomics Consortium (NESG) Target OR273

PDBID: 4JC0
TargetID: NESG-VR77
Title: Crystal structure of Thermotoga maritima holo RimO in complex with pentasulfide, Northeast Structural Genomics Consortium Target VR77

PDBID: 4JRF
TargetID: JCSG-417041
Title: Crystal structure of a putative cell adhesion protein (BACOVA_01548) from Bacteroides ovatus ATCC 8483 at 1.98 A resolution (PSI Community Target, Nakayama)

PDBID: 4J01
TargetID: MCSG-APC105002
Title: Crystal Structure of Fischerella Transcription Factor HetR complexed with 29mer DNA target

PDBID: 4J00
TargetID: MCSG-APC105002
Title: Crystal Structure of Fischerella Transcription Factor HetR complexed with 24mer DNA target

PDBID: 4IZZ
TargetID: MCSG-APC105002
Title: Crystal Structure of Fischerella Transcription Factor HetR complexed with 21mer DNA target

Click here to see all 501 structures

Questions regarding scientific proposals and issues, please contact Dr. Ward Smith.
Report any technical issues to cnt-comments@sbkb.org.