|Biological Search Options||Experimental Search Options||Ownership Search Options|
|Sequence||Reported Progress||Project Target ID|
|Cutoff E-Value||Materials Available||Centers|
|Source Organism||Trial Stop Status||PSI:Biology Partnerships|
|Macromolecule Name||Protocol Used||Project|
|Database ID||Target Updated||Result Format|
MKTIIALSYIFCLVFAQDLPGNDNNSTATLCLGHH AVPNGTLVKTITNDQIEVTNATELVQSSSTGKICN NPHRILDGINCTLIDALLGDPHCDGFQNEKWDLFV ERSKAFSNCYPYDVPDYASLRSLVASSGTLEFINE GFNWTGVTQNGGSSACKRGPDSGFFSRLNWLYKSG STYPVQNVTMPNNDNSDKLYIWGVHHPSTDKEQTN LYVQASGKVTVSTKRSQQTIIPNVGSRPWVRGLSS RISIYWTIVKPGDILVINSNGNLIAPRGYFKMRTG KSSI
It is useful, particularly when searching large databases, to know how likely (or rather unlikely) it is that an alignment could arise by chance. BLAST gives some measure of this with the E-value it supplies with each alignment.
As an example, "Expect = 1e-63" tells us that, at least as an approximation, the chance of an alignment as good or better than this occurring by chance is tiny (1e-63). By default BLAST shows alignments with E-values up to and including 10. An alignment with an E-value this high does not, in itself, mean very much as it is expected for the search to throw up around 10 matches of this quality or better purely by chance. (From http://www.clarkfrancis.com/blast/)
Autocomplete text search for the scientific name of the source organism from which a target sequence originated. Enter in the first few letters of a species to see what exists in the database. Continue typing to narrow your results and/or select an option from the resulting drop-down list.
TargetTrack requests depositions follow the nomenclature of the NCBI Taxonomy database.Examples:
|Database Name||Database ID (what to enter)|
Each target is registered as falling within a research-focus category. See drop-down list for current categories.
Select one or more target category values to customize your query.
Any experimental progress reported for a target. Currently accepted target status milestones are given as drop-down options.
Select one or more status values to obtain all targets that have reached that status in one or more of their trials. This query is useful when searching for targets that have reached a particular milestone and may be further along the production pipeline.
For example, select 'expressed' to return all targets that have been successfully expressed, without concern for their current production status.
Return targets that have experimental material available for use.
Clones Available - returns targets with one or more clones available at the PSI:Biology-Materials Repository.
Return targets that have one or more trials with the selected stop status. For example, select 'purification failed' for targets where protein cannot be isolated using attempted techniques. You can use this option to look for methods that led to unsuccessful returns so that you don't make the same mistakes in the lab.
Select one or more stop status values to customize your query.
The type of protocol provided in one or more trials of a target. Currently accepted protocol types are given as drop-down options.
Select one or more protocol type values to return targets that have the selected protocol types reported in one or more trials.
For example, select 'purification' to return targets which contain a purification protocol in their reported progress.
Returns targets that have been updated during the timeframe selected. The latest update of information on a target could include an update on any data associated with a target entry such as an experimental status change, modifications to the protein sequence, changes to external database references, etc.
Please note that the date may not always represent the date when a target was deposited to TargetTrack or the date of the latest experimental status. If you need help or have question about target status history, please contact email@example.com
|PSI Center||PSI Project|
|JCSG||PSI-1, PSI-2, PSI:Biology|
|MCSG||PSI-1, PSI-2, PSI:Biology|
|NESG||PSI-1, PSI-2, PSI:Biology|
|Short Name||Full Name||HT Partner|
|CEBS||Chaperone-Enabled Studies of Epigenetic Regulation Enzymes||NESG|
|CELLMAT||Assembly, Dynamics and Evolution of Cell-Cell and Cell-Matrix Adhesions||NYSGRC|
|CHSAM||Structure, Dynamics and Activation Mechanisms of Chemokine Receptors||GPCR|
|HOMEO||Structural Basis of Protein Homeostasis||NESG|
|IFN||Atoms-to-Animals: The Immune Function Network||NYSGRC|
|MPP||Mitochondrial Protein Partnership||NESG|
|MTBI||Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors||MCSG|
|NatPro||Enzyme Discovery for Natural Product Biosynthesis||MCSG|
|NHRs||Structural Features of the Nuclear Receptor Signaling Code||JCSG|
|NPCXstals||Nucleocytoplasmic Transport: a Target for Cellular Control||NYSGRC|
|PCSEP||Program for the Characterization of Secreted Effector Proteins||MCSG|
|STEMCELL||Partnership for Stem Cell Biology||JCSG|
|TCELL||Partnership for T-Cell Biology||JCSG|
|TJMP||Structure-Function Studies of Tight Junction Membrane Proteins||CSMP|
|UC4CDI||Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes||MCSG|
Some targets are listed as falling under one or more projects. See drop-down list for current projects available.
Select one or more projects to customize your query.
Features of selected targets are displayed in HTML format.
Sequences of selected targets are outputted in Pearson/FASTA format. Click link to download the .fa.zip fasta file to your computer.
XML Format (coming soon)
Features of selected target sequences are outputted in XML format.
The XML report format follows the recommendations of the Task Force on Target Tracking.