The crystal structure of EF-Tu bound to the 70S ribosome solves a 40-year-old puzzle.
Regulating nitrogen assimilation
By combining their efforts, researchers at two PSI centers provide new insights into a switch that controls nitrogen metabolism in microorganisms.
The structure of doublecortin bound to 13-protofilament microtubules helps build a model for understanding microtubule stabilization.
Fit for Export
How nuclear export signals (NESs) are recognized by their receptor CRM1 is now examined by a variety of approaches and shows that different NES peptides adopt different conformations to fit into five rigid hydrophobic binding pockets on CRM1, and redefines an NES consensus.
A new amphiphile for crystallizing membrane proteins
An easy-to-use chemical approach for stabilizing, extracting and crystallizing integral membrane proteins.
Predicting functions within a superfamily
A detailed analysis of the HUP superfamily provides the groundwork for automated function prediction.