PSI Structural Biology Knowledgebase

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this month's highlights

Synopses of important developments in the field of structural biology and structural genomics, including advances from the Protein Structure Initiative. The featured articles and technical highlights are specially written for the Structural Biology Knowledgebase, while the research highlights are taken from NPG publications.

June 2011

featured articles

Sugar transport
The structure of an EIIC from Bacillus cereus shows the architecture of this important class of sugar transporters.

 

Binding complement with complementarity
The structure of complement C3d with complement receptor 2 answers lingering questions about the interaction of these two proteins.

 

research highlights

Microbiology: Toxic turnover
Analysis of the PezAT system in Streptococcus pneumoniae gives insight into the mechanisms of PexT toxicity.

 

Bacterial physiology: Flipping lipids
FRET-based analysis of lipid translocation implicates the transmembrane protein FtsW as a flippase.

 

technical highlights

An easier solution for symmetry
A new method from the Rosetta suite allows for the determination of symmetric oligomeric protein structures in solution using primarily RDCs and chemical shifts.

 

Solutions in the solution
A high-throughput analysis demonstrates the complementary power of SAXS with other structural techniques.

 

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